Mortality in critically ill elderly individuals receiving mechanical ventilation

Researchers analyzed 21 studies to determine the impact of age on mortality in elderly subjects on mechanical ventilation. Eligible studies compared two different age groups. Mortality in subjects ages ≥ 65 years was considered the primary outcome, and the secondary outcomes included severity scores, intensive care unit and hospital lengths of stay, and the presence of ventilator-associated pneumonia. Via subgroup analysis, subjects with ARDS and of cutoff ages of 70 and 80 years were examined for mortality. Despite low-quality evidence, the investigators concluded that age may be associated with greater mortality in critically ill subjects receiving mechanical ventilation.

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